Make It Brain

lab mouse
Last month, the Allen Institute team successfully created a digital simulation of a mouse brain cortex, which the institute heralded as “one of the largest and most detailed simulations” of an animal brain ever. Photo: Abrice Coffrini/AFP/Getty Images)
Ian Krietzberg
December 9, 2025

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Everyone is entitled to their own version of happiness, and Dr. Anton Arkhipov has spent the past 12 years at the Allen Institute working to digitally replicate tens of thousands of miles of mouse brain circuitry. Last month, his team successfully created a digital simulation of a mouse brain cortex, which the Allen Institute heralded as “one of the largest and most detailed simulations” of an animal brain ever. Arkhipov described the achievement as a major milestone along a “very long and complicated path toward being able to simulate the brain in all its glorious complexity.” (The work builds on Europe’s Blue Brain Project.)